Certest Pharma

Certest Pharma is a cutting-edge, technology-driven company focused on developing a comprehensive platform for RNA and oligonucleotide therapeutics, with a strong emphasis on enhancing delivery and thermostability. A key area of expertise is the development of proprietary ionizable lipids, which are crucial for lipid nanoparticle (LNP) production and the systemic delivery of RNA therapeutics.

Certest Pharma offers a complete solution, leveraging its extensive experience in delivery technology:

• Delivery Technology: Through semi-rational design, Certest Pharma has selected over 1,000 proprietary ionizable lipids that demonstrate outstanding in vivo performance. These lipids have been used to develop LNPs with exceptional thermostability, enabling highly effective and tailored RNA delivery.
• Targeted Delivery: By utilizing a diverse range of ionizable lipids, Certest Pharma can achieve various extra-hepatic biodistribution profiles for RNA and oligonucleotide therapeutics. Additionally, a novel active targeting strategy, based on a proprietary peptide library, allows for fully customized delivery solutions.
• RNA and Oligonucleotide Platform: With over 20 years of expertise, Certest Pharma’s platform covers all critical stages of RNA and oligonucleotide therapeutic development, including design, synthesis, scale-up, and evaluation. The platform also features proprietary UTR sequence and codon optimization software, which enhances protein expression levels, alongside in-house developed enzymes for mRNA production.

Certest Pharma’s integrated and innovative approach positions it as a leader in the development of advanced therapeutics, offering bespoke solutions that meet the evolving demands of the biotech industry.

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